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Overview

Optimize Gastrointestinal Care with Precision Pharmacogenomics

Personalize treatments for diverse GI conditions, reduce adverse effects, and enhance patient outcomes across your health system.
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Overview
Gastrointestinal (GI) disorders can present complex challenges, as patients may respond differently to proton pump inhibitors, prokinetics, and other digestive therapies. PGxAI's Gastroenterology module (PGxChiron™) leverages advanced pharmacogenomics and real-world clinical data to guide optimal drug selection and dosing. By integrating each patient's genetic profile, PGxChiron™ helps gastroenterologists reduce treatment failures, minimize side effects, and improve long-term GI health outcomes.
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20+ GI drugs supported, including PPIs, antiemetics, and motility agents.
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15 key genetic markers analyzed for drug efficacy and metabolism.
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AI-driven insights updated in real time, maximizing therapeutic benefits for conditions such as GERD, IBD, and IBS.
Key Highlights
Serving every stakeholder in healthcare
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Improved Motility Management
Tailored regimens for Cisapride, Domperidone, and other motility agents, enhancing GI transit and patient quality of life.
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Reduced Nausea & Vomiting
AI-guided antiemetic choices (Ondansetron, Granisetron, Tropisetron) help minimize treatment delays and patient discomfort.
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Targeted PPI Therapy
Personalized selection and dosing of agents like Omeprazole, Pantoprazole, and Esomeprazole to reduce acid reflux complications.
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Reimbursable PGx Testing
Built around recognized CPT codes, enabling cost-effective, personalized gastroenterology.
Clinical Impact
Maximize Clinical Impact with PGxAI
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Precision-Guided Therapy Optimization
PGxAI mines genotype, phenotype, and comorbidity data in real time to recommend the optimal drug–dose pair at the first prescription. By accounting for actionable allelic variants and metabolic phenotypes, it minimizes trial-and-error titration and sharply reduces severe drug–gene and drug–drug interactions.
Superior Patient Outcomes & Experience
Genomically informed prescribing lowers adverse-event rates, accelerates therapeutic response, optimizes co-administered medications and boosts adherence. Patients spend less time managing side effects and more time benefiting from treatment, enhancing both clinical endpoints and satisfaction metrics across specialties.
Demonstrable Value-Based Performance
Fewer complications, shorter lengths of stay, and reduced readmissions translate into measurable gains on CMS and private-payer quality dashboards. Institutions leveraging PGxAI can document higher quality scores and capture value-based reimbursement upside while lowering total cost of care.
Seamless Team Integration & Scalability
The platform embeds directly into leading EHRs and e-prescribing systems, delivering concise, guideline-aligned reports that support rapid decision-making for multidisciplinary teams. Standardized APIs and CDS hooks allow effortless expansion from pilot units to enterprise-wide deployment without workflow disruption.
Drug Categories
PGxAI supports a wide range of GI therapies
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Proton Pump Inhibitors (PPIs):
Omeprazole, Pantoprazole, Esomeprazole
Antiemetic Therapies:
Ondansetron, Granisetron, Tropisetron
Motility Agents:
Cisapride, Domperidone, Itopride
Gastrointestinal Protectants:
Sucralfate, Misoprostol
Cannabinoid-Based Treatments:
Dronabinol (for refractory nausea and appetite stimulation) Each recommendation draws on validated genetic markers (e.g., CYP2C19, CYP3A4) and real-world clinical data.
Case Study
Lakeside GI Clinic
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Challenge
High rates of incomplete relief in GERD patients, resulting in repeated endoscopies and escalating treatment costs.
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Solution
PGxChiron™ integrated to align PPI choices with each patient's genetic profile, optimizing acid suppression.
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Results
25% decrease in unresolved GERD cases over 6 months, fewer follow-up endoscopies, and better patient satisfaction scores.
What's next
Ready to Shape the Future of Precision Medicine?
Empower your gastroenterology team with AI-driven pharmacogenomics that curb treatment failures, cut unnecessary expenses, and streamline patient care.
Contact Our Gastroenterology Team
Discuss integration options and pilot programs.
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Request a Demo
See how PGxChiron™ enhances GI workflows.
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