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Providers Metabolism
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Overview

Optimize Metabolic Health with Precision Pharmacogenomics

Personalize GLP-1 therapies and weight management solutions to improve outcomes and reduce complications across your health system.
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Overview
Metabolic disorders—including obesity, type 2 diabetes, and related complications—require a highly individualized approach for effective and sustainable results. PGxAI’s Metabolism module (PGxMetis™) leverages advanced pharmacogenomics and real-world data to guide therapy selection and dosing for GLP-1 receptor agonists, appetite suppressants, and other metabolic treatments. By aligning each patient’s genetic profile with the right medication strategy, PGxMetis™ supports better glycemic control, targeted weight loss, and improved long-term health outcomes.
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Covers a wide array of therapies, from GLP-1 agonists (e.g., semaglutide, liraglutide) to lipase inhibitors and anorexiants.
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Integrates 12+ critical genetic markers associated with metabolic pathways and drug metabolism.
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AI-driven insights updated in real time, enhancing efficacy while minimizing adverse effects.
Key Highlights
Serving every stakeholder in healthcare
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Comprehensive GLP-1 Analysis
Evaluates genetic factors influencing response to semaglutide, liraglutide, and dual agonists like tirzepatide.
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Customized Weight-Management Protocols
Integrates pharmacogenetic data for orlistat, phentermine-topiramate, and naltrexone-bupropion, ensuring efficient, personalized outcomes.
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Reduced Adverse Events
Tailored dosing strategies help mitigate side effects such as gastrointestinal discomfort or hypoglycemia, improving patient adherence.
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EHR-Integrated Workflow
PGxMetis™ seamlessly merges with popular EHR systems, enabling clinicians to access real-time AI alerts and dosage guidance without disrupting routine.
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Reimbursable Testing
Many PGx analyses qualify under recognized CPT codes, streamlining billing for personalized metabolic care.
Clinical Impact
Serving every stakeholder in healthcare
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Lower Readmissions & Complications
By personalizing therapy, PGxMetis™ reduces hospital admissions related to severe glycemic events or weight-related comorbidities.
Improved Patient Engagement
Faster, more effective results in weight management and diabetes control enhance patient motivation and compliance.
Streamlined Provider Coordination
Endocrinologists, dietitians, and primary care providers share unified PGx data, ensuring consistent treatment decisions.
Value-Based Care Alignment
Better metabolic outcomes and fewer complications support higher quality metrics and potential reimbursement benefits.
Drug Categories
PGxAI supports a range of metabolic and weight-management therapies
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GLP-1 Receptor Agonists:
Semaglutide, Tirzepatide, Liraglutide
Gastrointestinal Lipase Inhibitors:
Orlistat
Anorexiants:
Phentermine-Topiramate, Naltrexone-Bupropion
Melanocortin Receptor Agonists:
Setmelanotide
Adjunctive Agents:
Caffeine, Ephedrine (if clinically appropriate). Each recommendation is grounded in validated genetic research (e.g., MC4R, FTO variants) and real-world clinical data.
Integration
Seamless EHR Integration
PGxMetis™ is built for enterprise-level scalability:
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Security
HIPAA & SOC 2 compliance ensures patient privacy and data integrity.
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Automations
Automated alerts for high-risk gene-drug interactions.
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Analytics
Customizable dashboards for oncology pharmacists, oncologists, and care coordinators.
Case Study
Evergreen Metabolic Center
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Challenge
Low response rates to standard GLP-1 therapies and frequent dropout due to side effects.
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Solution
PGxMetis™ integrated to identify optimal candidates for semaglutide vs. other GLP-1s, tailoring dosages based on genetic markers.
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Results
35% improvement in average weight loss at 6 months, lower incidence of GI side effects, and higher patient retention.
“PGxAI has allowed us to fine-tune our weight-management protocols, enhancing both efficacy and patient satisfaction. It’s a key step toward truly personalized metabolic care.”
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Dr. Maria Daniels
Medical Director, Evergreen Metabolic
Whats next
Ready to Shape the Future of Precision Medicine?
Empower your metabolic care teams with AI-driven pharmacogenomics that minimize side effects, boost treatment efficacy, and transform patient outcomes.
Contact Our Metabolism Team
Discuss pilot programs and tailored EHR integration.
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Request a Demo
Explore PGxMetis™ in action for your metabolic workflows.
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Learn More About EHR Integration
Discover secure, scalable interoperability solutions.
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